Sensitivity of an image plate system in the XUV (60 eV < E < 900 eV)

Phosphor imaging plates (IPs) have been calibrated and proven useful for quantitative x-ray imaging in the 1 to over 1000 keV energy range. In this paper we report on calibration measurements made at XUV energies in the 60 to 900 eV energy range using beamline 6.3.2 at the Advanced Light Source at Lawrence Berkeley National Laboratory. We measured a sensitivity of ~25 plus or minus 15 counts/pJ over the stated energy range which is compatible with the sensitivity of Si photodiodes that are used for time-resolved measurements. Our measurements at 900 eV are consistent with the measurements made by Meadowcroft et al. at ~1 keV.Comment: 7 pages, 2 figure

Transient x-ray diffraction used to diagnose shock compressed Si crystals on the Nova laser

Transient x-ray diffraction is used to record time-resolved information about the shock compression of materials. This technique has been applied on Nova shock experiments driven using a hohlraum x-ray drive. Data were recorded from the shock release at the free surface of a Si crystal, as well as from Si at an embedded ablator/Si interface. Modeling has been done to simulate the diffraction data incorporating the strained crystal rocking curves and Bragg diffraction efficiencies. Examples of the data and post-processed simulations are presented

Developing solid state experiments on the Nova laser

An x-ray drive has been developed to shock compress metal foils in the solid state using an internally shielded hohlraum with a high contrast shaped pulse from the Nova laser. The drive has been characterized and hydrodynamics experiments designed to study growth of the Rayleigh-Taylor (RT) instability in Cu foils at 3 Mbar peak pressures in the plastic flow regime have been started. Pre-imposed modulations with an initial wavelength of 20-50 {micro}m, and amplitudes of 1.0-2.5 {micro}m show growth consistent with simulations. In the Nova experiments, the fluid and solid states are expected to behave similarly for Cu. An analytic stability analysis is used to motivate an experimental design with an Al foil where the effects of material strength on the RT growth are significantly enhanced. The conditions reached in the metal foils at peak compression are similar to those predicted at the core of the earth

Molecular Signatures Reveal Circadian Clocks May Orchestrate the Homeorhetic Response to Lactation

Genes associated with lactation evolved more slowly than other genes in the mammalian genome. Higher conservation of milk and mammary genes suggest that species variation in milk composition is due in part to the environment and that we must look deeper into the genome for regulation of lactation. At the onset of lactation, metabolic changes are coordinated among multiple tissues through the endocrine system to accommodate the increased demand for nutrients and energy while allowing the animal to remain in homeostasis. This process is known as homeorhesis. Homeorhetic adaptation to lactation has been extensively described; however how these adaptations are orchestrated among multiple tissues remains elusive. To develop a clearer picture of how gene expression is coordinated across multiple tissues during the pregnancy to lactation transition, total RNA was isolated from mammary, liver and adipose tissues collected from rat dams (n = 5) on day 20 of pregnancy and day 1 of lactation, and gene expression was measured using Affymetrix GeneChips. Two types of gene expression analysis were performed. Genes that were differentially expressed between days within a tissue were identified with linear regression, and univariate regression was used to identify genes commonly up-regulated and down-regulated across all tissues. Gene set enrichment analysis showed genes commonly up regulated among the three tissues enriched gene ontologies primary metabolic processes, macromolecular complex assembly and negative regulation of apoptosis ontologies. Genes enriched in transcription regulator activity showed the common up regulation of 2 core molecular clock genes, ARNTL and CLOCK. Commonly down regulated genes enriched Rhythmic process and included: NR1D1, DBP, BHLHB2, OPN4, and HTR7, which regulate intracellular circadian rhythms. Changes in mammary, liver and adipose transcriptomes at the onset of lactation illustrate the complexity of homeorhetic adaptations and suggest that these changes are coordinated through molecular clocks

Hot dens% millimeter-scale,high-Z plasmas for laser-plasma interactions studies ..,: $ii

We have designed and produced hot, millimeter-scale, high-Z plasmas of interest for National I~tion Facility hohkaum target design. Using a high-Z gas till produces electron temperatures in the 3.5-6-keV range, i b the highest temperatures measured to date for high-density ( l&amp;l e/cm3) laser-heated plasmas, and much higher than the 3 keV found for low-Z (neopentane) tills. These measurements are in good agreement with the target design calculations, and the Lshell spectroscopic approach used to estimate me elwx.ron temperature has certain advantages over traditional K-shell approaches. [S1063-65 1

Plasma evolution from laser‐driven gold disks. I. Experiments and results

Gold disk targets were irradiated with green (λ=0.53 μm) laser light at intensities between 0.5 and 5×1014 W/cm2 using shaped laser pulses. Plasma conditions near and below critical density (nc≂4×1021/cm3) were determined from three diagnostics. Streaked one‐dimensional images of the M‐band emission (2–3.5 keV) along the laser axis yield the peak emission trajectory. Temporally and spatially averaged measurements of the hard x‐ray spectrum (4–25 keV) were used to determine the average coronal electron temperature. Holographic interferometry was used to determine the electron density profiles and scale lengths along the laser axis. The peak emission trajectory, electron temperature, and scale lengths are all in good agreement with simulations, but the magnitudes of the electron density profiles are not, as discussed in an accompanying paper [Phys. Fluids B 2, 2448 (1990)].Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71319/2/PFBPEI-2-10-2437-1.pd